Featured posters
Gelatin for 3D bioprinting and tissue engineering
Gelatin is a popular choice of biomaterial for bioprinting research. Rousselot’s X-Pure® gelatin stands out with unparalleled purity and customizable properties, enabling researchers to translate their research into clinical applications.
Insights
A medical revolution: 3D bioprinting
Emerging technologies like 3D bioprinting bring new options for developing treatments to repair or regenerate injured and diseased tissues and organs.
X-Pure for 3D bioprinting and tissue engineering
The X-Pure range, which includes the photocurable gelatins X-Pure GelMA and GelDAT, offers tunable physicochemical properties. Rousselot provides a variety of gelatins that can be used to produce RGD-rich matrices with varying stiffness, ranging from soft intestinal tissues to hard bony structures.
Unique functionalities and properties
Why choose X-Pure?
Compliance
All X-Pure gelatins meet the requirements of major pharmacopoeias and support regulatory compliance with the EU Medical Device Regulation (MDR) 2017/745 and ISO 22442. These materials offer full traceability, readily available documentation, and validated viral inactivation, streamlining the path to clinical use.
Consistency
With X-Pure, there's no need to adjust your printer settings when receiving a new batch, providing seamless consistency and ease of use. X-Pure helps eliminate data variability, ensuring reproducible and consistent results for efficient clinical translation while supporting the biocompatibility and biodegradability of your final application. X-Pure gelatins, including GelMA, are thermostable at 37°C, purified, and consistently produced under GMP conditions.1
High purity
Pyrogens that can be found in food-grade gelatin can cause inflammation when directly introduced in the body. Impurities may also skew cellular responses.2 X-Pure, with ultra-low endotoxin levels (≤10 EU/g), maintains natural cell activity, making it ideal for even the most sensitive in vivo applications.
Customizable mechanical properties
X-Pure is customizable, allowing you to recreate the specific mechanical cues of a cell's natural extracellular matrix and precisely control biodegradability. Compressive and elastic moduli range from a few kPa to several hundred kPa, and degradation times can vary from days to months. See Figure 1.
Figure 1: Customizable mechanical properties
Medical grade gelatins
Discover our X-Pure solutions
Expert services
Worldwide support and expertise
Take advantage of our expert services to help select the right gelatin and formulate with ease.
Stem cell proliferation on 3D printed discs improved with low endotoxin and low molecular weight gelatin coating
How to create the perfect GelMA formulation for specific applications: A story of temperature and photo-crosslinking
Jan-Philip Zegwaart, Thomas Van Gansbeke, Catarina Ferreira da Silva, Riccardo Levato & Jos Olijve
Links
Additional information
Webshop (research and technical grades)
*Please note, by accessing the Webshop you will be redirected to a third party website. Rousselot is not liable for its content or the products/services offered on any third party website.
References
- IPEC. Excipient Good Manufacturing Practices Guide, 2022
- Heinrich, M.A., M. Mangia, and J. Prakash. 2021. Impact of endotoxins on bioengineered tissues and models. Trends Biotechnol.