Doctor Roberto Zagury
Zagury currently works across three key areas. He leads the Department of Exercise, Sports and Diabetes at the Brazilian Diabetes Society, overseeing a team of doctors, endocrinologists and physical educators. In addition to this work, Dr. Zagury maintains a private practice and serves as a federal government doctor at an endocrinology institute.
Supplements can help manage post-meal blood sugar spikes, says endocrinologist Doctor Robert Zagury
Our blood sugar is vital to our health, and Doctor Roberto Zagury, a Brazilian endocrinologist, is recognized for his expertise in this field. In this interview, Dr. Zagury shares his insight into blood sugar, the post-meal spike and the synergy between diet, supplements and medicine.
What is the post-meal blood sugar spike?
"When we eat, our body breaks the food down into glucose, which then enters the bloodstream. The resulting natural rise in blood sugar after eating is called a post-meal blood sugar spike. The level of the spike depends on what is on your plate. For example, eating foods high in sugar or simple carbs—like pastries or white bread—can cause a sharp rise in blood sugar. On the other hand, balanced meals that include fiber, protein and healthy fats tend to slow down this process, leading to a smaller, more stable increase.
While small spikes within a certain range are normal, spikes that exceed the upper limit may become a health concern over time. These high fluctuations in blood glucose throughout the day can negatively impact our physical and mental well-being, contributing to issues such as cravings, energy dips and unhealthy eating patterns. Over time, they may increase the risk of metabolic and cardiovascular diseases, even in otherwise healthy individuals (Belli et al., 2023).
That’s why it’s helpful to be mindful of your lifestyle and how it affects your blood sugar."
Who should think about the post-meal blood sugar spike?
“The post-meal blood sugar spike is a natural process through which the body fuels itself with energy and nutrients. However, three groups of healthy individuals may benefit from a proactive approach to glucose control:
- Active individuals
- Overweight individuals
- Glucose-conscious individuals
For all three groups, adopting non-pharmacological strategies can help support overall health. These strategies can include eating nutritious, balanced meals, engaging in regular exercise and using science-backed supplements.”
How can supplements help manage blood sugar spikes?
“Supplements are becoming an increasingly popular option for managing blood glucose levels. Many people, including my patients, prefer trying supplements over drugs. Supplements often feel like a more natural and approachable solution, especially for those concerned about potential side effects.
One exciting research area has shown that a specific composition of collagen peptides can help control glucose spikes by stimulating the secretion of GLP-1 (glucagon-like peptide-1). GLP-1 is a hormone released by specialized cells in the intestine in response to food.
GLP-1 plays a crucial role in managing blood sugar after meals. When glucose levels rise, GLP-1 stimulates the pancreas to produce insulin, which lowers blood sugar. Simultaneously, it reduces the secretion of glucagon, a hormone that raises blood sugar.
Beyond glucose control, GLP-1 offers additional benefits. It slows stomach emptying, helping you feel full longer and acts on the hypothalamus—an area of the brain that regulates appetite—to promote satiety. These combined effects not only help manage blood sugar but also support weight control.”
What does the science say about supplements for blood glucose control?
“Alongside the global hype around GLP-1-based medications, we are seeing new supplements emerge that boost GLP-1. Research has shown that Nextida® GC, a new ingredient launched by Rousselot, shows promising potential in this area.
The first proof-of-concept study published in a peer-reviewed journal demonstrated that Nextida GC reduced post-meal glucose spike levels by an average of 42% (Grassett et al., 2024). Research has also shown that Nextida GC triggered a natural GLP-1 response. Importantly, no adverse effects were reported.
A non-pharmacological alternative like Nextida GC shows potential to smooth out post-meal glucose spikes, making blood sugar management easier for those consumer groups I mentioned earlier, who are active, overweight, or glucose conscious. While maintaining a balanced diet and avoiding sugary foods is ideal, for most of us it is normal to indulge occasionally. Having a practical tool like this to improve glucose control can be a valuable addition to someone’s healthcare routine."
Discover more about the research into Nextida GC
How do you take Nextida GC?
“When using Nextida GC, I would recommend following the approach tested in the clinical trials: take it 30 minutes before a meal. For example, if you are planning your breakfast, mix the powder with water and drink it about 30 minutes beforehand. An additional benefit is also an increased protein intake.”
What is your own experience with Nextida GC?
“I recently saw a healthy patient who wanted to be proactive about managing her blood sugar levels. In a case like this, I offered her Nextida GC as a gentle, non-pharmacological option. This is the first time I have used Nextida GC with a patient and it is exciting to use this supplement in a real-world setting. I look forward to sharing more insights as we continue exploring its potential in managing post-meal blood sugar spikes.”
For more from Dr. Zagury, follow him on Instagram, @robertzagury, or visit his website.
Or find out how Nextida GC supports post-meal blood sugar spike control.
Rousselot makes no representation or warranty, whether expressed or implied, as to the accuracy, reliability, or completeness of the information, nor does it assume any legal liability, whether direct or indirect, for any information. Use of this information shall be at your discretion and risk. Nothing herein relieves you from carrying out your own suitability determinations and tests and from your obligation to comply with all applicable laws and regulations and to observe all third-party rights. This product is not intended to diagnose, treat, cure, or prevent any disease.
This presentation refers to market and/or research data in general and does not imply any direct link between the subjects mentioned and Rousselot’s products.
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